| Tijuana | - | 21 oct 21:00 hrs | - | Chiapas | ||
| Cruz Azul | - | 22 oct 17:00 hrs | - | Puebla | ||
| Querétaro | - | 22 oct 19:00 hrs | - | América | ||
| Monterrey | - | 22 oct 19:00 hrs | - | Toluca | ||
| León | - | 22 oct 21:00 hrs | - | Morelia | ||
| Necaxa | - | 22 oct 21:00 hrs | - | Veracruz | ||
| Pumas UNAM | - | 23 oct 12:00 hrs | - | Tigres UANL | ||
| Santos Laguna | - | 23 oct 18:00 hrs | - | Atlas | ||
| Guadalajara | - | 23 oct 20:00 hrs | - | Pachuca |
| Potros UAEM | - | 21 oct 19:00 hrs | - | Venados | ||
| Coras de Tepic | - | 21 oct 21:30 hrs | - | Atlante | ||
| Murciélagos | - | 21 oct 22:05 hrs | - | Cafetaleros de Tapachula | ||
| Cimarrones de Sonora | - | 21 oct 22:36 hrs | - | Correcaminos UAT | ||
| Lobos BUAP | - | 22 oct 17:00 hrs | - | Celaya | ||
| Loros Universidad | - | 22 oct 19:00 hrs | - | Alebrijes de Oaxaca | ||
| Juárez | - | 22 oct 20:00 hrs | - | Zacatepec Siglo XXI | ||
| Tampico Madero | - | 22 oct 20:00 hrs | - | Mineros de Zacatecas | ||
| Universidad Guadalajara | - | 23 oct 12:00 hrs | - | Dorados |
| AFC Bournemouth | - | 22 oct 06:30 hrs | - | Tottenham Hotspur | ||
| Arsenal | - | 22 oct 09:00 hrs | - | Middlesbrough | ||
| Burnley | - | 22 oct 09:00 hrs | - | Everton | ||
| Hull City | - | 22 oct 09:00 hrs | - | Stoke City | ||
| Leicester City | - | 22 oct 09:00 hrs | - | Crystal Palace | ||
| Swansea City | - | 22 oct 09:00 hrs | - | Watford | ||
| West Ham United | - | 22 oct 09:00 hrs | - | Sunderland | ||
| Liverpool | - | 22 oct 11:30 hrs | - | West Bromwich Albion | ||
| Manchester City | - | 23 oct 07:30 hrs | - | Southampton | ||
| Chelsea | - | 23 oct 10:00 hrs | - | Manchester United |
| Hamburger SV | - | 21 oct 13:30 hrs | - | Eintracht Frankfurt | ||
| Bayer Leverkusen | - | 22 oct 08:30 hrs | - | Hoffenheim | ||
| Hertha BSC | - | 22 oct 08:30 hrs | - | Köln | ||
| Ingolstadt | - | 22 oct 08:30 hrs | - | Borussia Dortmund | ||
| Darmstadt 98 | - | 22 oct 08:30 hrs | - | Wolfsburg | ||
| Freiburg | - | 22 oct 08:30 hrs | - | Augsburg | ||
| Bayern München | - | 22 oct 11:30 hrs | - | Borussia M'gladbach | ||
| RB Leipzig | - | 23 oct 08:30 hrs | - | Werder Bremen | ||
| Schalke 04 | - | 23 oct 10:30 hrs | - | Mainz 05 |
| Sampdoria | - | 22 oct 11:00 hrs | - | Genoa | ||
| Milan | - | 22 oct 13:45 hrs | - | Juventus | ||
| Udinese | - | 23 oct 05:30 hrs | - | Pescara | ||
| Atalanta | - | 23 oct 08:00 hrs | - | Internazionale | ||
| Cagliari | - | 23 oct 08:00 hrs | - | Fiorentina | ||
| Crotone | - | 23 oct 08:00 hrs | - | Napoli | ||
| Empoli | - | 23 oct 08:00 hrs | - | Chievo | ||
| Torino | - | 23 oct 08:00 hrs | - | Lazio | ||
| Bologna | - | 23 oct 11:00 hrs | - | Sassuolo | ||
| Roma | - | 23 oct 13:45 hrs | - | Palermo |
| Osasuna | - | 21 oct 13:45 hrs | - | Real Betis | ||
| Espanyol | - | 22 oct 06:00 hrs | - | Eibar | ||
| Valencia | - | 22 oct 09:15 hrs | - | Barcelona | ||
| Real Sociedad | - | 22 oct 11:30 hrs | - | Deportivo Alavés | ||
| Granada | - | 22 oct 13:45 hrs | - | Sporting Gijón | ||
| Celta de Vigo | - | 23 oct 05:00 hrs | - | Deportivo La Coruña | ||
| Sevilla | - | 23 oct 09:15 hrs | - | Atlético Madrid | ||
| Villarreal | - | 23 oct 11:30 hrs | - | Las Palmas | ||
| Málaga | - | 23 oct 11:30 hrs | - | Leganés | ||
| Real Madrid | - | 23 oct 13:45 hrs | - | Athletic Club |
| Monaco | - | 21 oct 13:45 hrs | - | Montpellier | ||
| Olympique Lyonnais | - | 22 oct 10:00 hrs | - | Guingamp | ||
| Bordeaux | - | 22 oct 13:00 hrs | - | Nancy | ||
| Lille | - | 22 oct 13:00 hrs | - | Bastia | ||
| Dijon | - | 22 oct 13:00 hrs | - | Lorient | ||
| Angers | - | 22 oct 13:00 hrs | - | Toulouse | ||
| Nantes | - | 22 oct 13:00 hrs | - | Rennes | ||
| Caen | - | 23 oct 08:00 hrs | - | Saint-Étienne | ||
| Metz | - | 23 oct 10:00 hrs | - | Nice | ||
| PSG | - | 23 oct 13:45 hrs | - | Olympique Marseille |
| Excelsior | - | 21 oct 13:00 hrs | - | PEC Zwolle | ||
| Go Ahead Eagles | - | 22 oct 11:30 hrs | - | Twente | ||
| PSV | - | 22 oct 12:45 hrs | - | Sparta Rotterdam | ||
| Roda JC | - | 22 oct 12:45 hrs | - | ADO Den Haag | ||
| Willem II | - | 22 oct 13:45 hrs | - | Utrecht | ||
| NEC | - | 23 oct 05:30 hrs | - | Vitesse | ||
| Feyenoord | - | 23 oct 07:30 hrs | - | Ajax | ||
| Groningen | - | 23 oct 07:30 hrs | - | AZ | ||
| Heerenveen | - | 23 oct 09:45 hrs | - | Heracles |
| La Equidad | - | 21 oct 19:45 hrs | - | Boyacá Chicó | ||
| Patriotas Boyacá | - | 22 oct 14:00 hrs | - | Fortaleza | ||
| Alianza Petrolera | - | 22 oct 16:00 hrs | - | Jaguares de Córdoba | ||
| Deportivo Cali | - | 22 oct 17:00 hrs | - | Junior | ||
| Deportivo Pasto | - | 22 oct 18:00 hrs | - | Rionegro Águilas | ||
| Medellín | - | 22 oct 20:00 hrs | - | Atlético Nacional | ||
| Atlético Huila | - | 23 oct 15:15 hrs | - | Once Caldas | ||
| Santa Fe | - | 23 oct 17:00 hrs | - | Deportes Tolima | ||
| Envigado | - | 23 oct 17:30 hrs | - | Atlético Bucaramanga | ||
| Cortuluá | - | 23 oct 19:30 hrs | - | Millonarios |
